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Tag 'Medical research'

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Conception to birth -- visualized

Image-maker Alexander Tsiaras shares a powerful medical visualization, showing human development from conception to birth and beyond. (Some graphic images.)

Is the obesity crisis hiding a bigger problem?

As a young surgeon, Peter Attia felt contempt for a patient with diabetes. She was overweight, he thought, and thus responsible for the fact that she needed a foot amputation. But years later, Attia received an unpleasant medical surprise that led him to wonder: is our understanding of diabetes right? Could the precursors to diabetes cause obesity, and not the

We can now edit our DNA. But let's do it wisely

Geneticist Jennifer Doudna co-invented a groundbreaking new technology for editing genes, called CRISPR-Cas9. The tool allows scientists to make precise edits to DNA strands, which could lead to treatments for genetic diseases … but could also be used to create so-called "designer babies." Doudna reviews how CRISPR-Cas9 works — and asks the scientific community to

What happens when you have a disease doctors can't diagnose

Five years ago, TED Fellow Jennifer Brea became progressively ill with myalgic encephalomyelitis, commonly known as chronic fatigue syndrome, a debilitating illness that severely impairs normal activities and on bad days makes even the rustling of bed sheets unbearable. In this poignant talk, Brea describes the obstacles she's encountered in seeking treatment for her

Body parts on a chip

It's relatively easy to imagine a new medicine, a better cure for some disease. The hard part, though, is testing it, and that can delay promising new cures for years. In this well-explained talk, Geraldine Hamilton shows how her lab creates organs and body parts on a chip, simple structures with all the pieces essential to testing new medications -- even

Could tissue engineering mean personalized medicine?

Each of our bodies is utterly unique, which is a lovely thought until it comes to treating an illness -- when every body reacts differently, often unpredictably, to standard treatment. Tissue engineer Nina Tandon talks about a possible solution: Using pluripotent stem cells to make personalized models of organs on which to test new drugs and treatments, and storing

A temporary tattoo that brings hospital care to the home

What if doctors could monitor patients at home with the same degree of accuracy they'd get during a stay at the hospital? Bioelectronics innovator Todd Coleman shares his quest to develop wearable, flexible electronic health monitoring patches that promise to revolutionize healthcare and make medicine less invasive.

Ultrasound surgery -- healing without cuts

Imagine having a surgery with no knives involved. At TEDMED, Yoav Medan shares a technique that uses MRI to find trouble spots and focused ultrasound to treat such issues as brain lesions, uterine fibroids and several kinds of cancerous growths.

A prosthetic eye to treat blindness

At TEDMED, Sheila Nirenberg shows a bold way to create sight in people with certain kinds of blindness: by hooking into the optic nerve and sending signals from a camera direct to the brain.

Beware conflicts of interest

In this short talk, psychologist Dan Ariely tells two personal stories that explore scientific conflict of interest: How the pursuit of knowledge and insight can be affected, consciously or not, by shortsighted personal goals. When we're thinking about the big questions, he reminds us, let's be aware of our all-too-human brains.

The coming crisis in antibiotics

Antibiotic drugs save lives. But we simply use them too much — and often for non-lifesaving purposes, like treating the flu and even raising cheaper chickens. The result, says researcher Ramanan Laxminarayan, is that the drugs will stop working for everyone, as the bacteria they target grow more and more resistant. He calls on all of us (patients and doctors alike)

Building the musical muscle

Charles Limb performs cochlear implantation, a surgery that treats hearing loss and can restore the ability to hear speech. But as a musician too, Limb thinks about what the implants lack: They don't let you fully experience music yet. (There's a hair-raising example.) At TEDMED, Limb reviews the state of the art and the way forward.

Treating cancer with electric fields

Surgery, chemotherapy and radiation are the best-known methods for treating cancer. At TEDMED, Bill Doyle presents a new approach, called Tumor Treating Fields, which uses electric fields to interrupt cancer cell division. Still in its infancy -- and approved for only certain types of cancer -- the treatment comes with one big benefit: quality of life.

On the virtual dissection table

Onstage at TED2012, Jack Choi demonstrates a powerful tool for training medical students: a stretcher-sized multi-touch screen of the human body that lets you explore, dissect and understand the body's parts and systems.

Print your own medicine

Chemist Lee Cronin is working on a 3D printer that, instead of objects, is able to print molecules. An exciting potential long-term application: printing your own medicine using chemical inks.

The promise of research with stem cells

Calling them "our bodies' own repair kits," Susan Solomon advocates research using lab-grown stem cells. By growing individual pluripotent stem cell lines, her team creates testbeds that could accelerate research into curing diseases -- and perhaps lead to individualized treatment, targeted not just to a particular disease but a particular person.

Why genetic research must be more diverse

Ninety-six percent of genome studies are based on people of European descent. The rest of the world is virtually unrepresented — and this is dangerous, says geneticist and TED Fellow Keolu Fox, because we react to drugs differently based on our genetic makeup. Fox is working to democratize genome sequencing, specifically by advocating for indigenous populations to get

Open-source cancer research

How does cancer know it's cancer? At Jay Bradner's lab, they found a molecule that might hold the answer, JQ1 -- and instead of patenting JQ1, they published their findings and mailed samples to 40 other labs to work on. An inspiring look at the open-source future of medical research.

We need better drugs -- now

Today we know the molecular cause of 4,000 diseases, but treatments are available for only 250 of them. So what’s taking so long? Geneticist and physician Francis Collins explains why systematic drug discovery is imperative, even for rare and complex diseases, and offers a few solutions -- like teaching old drugs new tricks.

Good news in the fight against pancreatic cancer

Anyone who has lost a loved one to pancreatic cancer knows the devastating speed with which it can affect an otherwise healthy person. TED Fellow and biomedical entrepreneur Laura Indolfi is developing a revolutionary way to treat this complex and lethal disease: a drug delivery device that acts as a cage at the site of a tumor, preventing it from spreading and

What doctors can learn from each other

Different hospitals produce different results on different procedures. Only, patients don’t know that data, making choosing a surgeon a high-stakes guessing game. Stefan Larsson looks at what happens when doctors measure and share their outcomes on hip replacement surgery, for example, to see which techniques are proving the most effective. Could health care

We can start winning the war against cancer

Learn about the latest advances in the war against cancer from Stanford researcher Adam de la Zerda, who's working on some cutting-edge techniques of his own. Using a remarkable imaging technology that illuminates cancer-seeking gold particles injected into the body, de la Zerda's lab hopes to light the way for surgeons to remove even the tiniest trace of deadly

The single biggest health threat women face

Surprising, but true: More women now die of heart disease than men, yet cardiovascular research has long focused on men. Pioneering doctor C. Noel Bairey Merz shares what we know and don't know about women's heart health -- including the remarkably different symptoms women present during a heart attack (and why they're often missed).

Saving faces

Facial surgeon Iain Hutchison works with people whose faces have been severely disfigured. By pushing to improve surgical techniques, he helps to improve their lives; and by commissioning their portraits, he celebrates their humanity. NOTE: This talk contains images of disfigured and badly injured faces that may be disturbing -- and Hutchison provides thoughtful

Alzheimer's is not normal aging — and we can cure it

More than 40 million people worldwide suffer from Alzheimer's disease, and that number is expected to increase drastically in the coming years. But no real progress has been made in the fight against the disease since its classification more than 100 years ago. Scientist Samuel Cohen shares a new breakthrough in Alzheimer's research from his lab as well as a message

Could a drug prevent depression and PTSD?

The path to better medicine is paved with accidental yet revolutionary discoveries. In this well-told tale of how science happens, neuroscientist Rebecca Brachman shares news of a serendipitous breakthrough treatment that may prevent mental disorders like depression and PTSD from ever developing. And listen for an unexpected — and controversial — twist.

A new way to heal hearts without surgery

At the intersection of medical invention and indigenous culture, pediatric cardiologist Franz Freudenthal mends holes in the hearts of children across the world, using a device born from traditional Bolivian loom weaving. "The most complex problems in our time," he says, "can be solved with simple techniques, if we are able to dream."

The brain may be able to repair itself — with help

Through treating everything from strokes to car accident traumas, neurosurgeon Jocelyne Bloch knows the brain's inability to repair itself all too well. But now, she suggests, she and her colleagues may have found the key to neural repair: Doublecortin-positive cells. Similar to stem cells, they are extremely adaptable and, when extracted from a brain, cultured and

A new superweapon in the fight against cancer

Cancer is a very clever, adaptable disease. To defeat it, says medical researcher and educator Paula Hammond, we need a new and powerful mode of attack. With her colleagues at MIT, Hammond engineered a nanoparticle one-hundredth the size of a human hair that can treat the most aggressive, drug-resistant cancers. Learn more about this molecular superweapon and join

How young blood might help reverse aging. Yes, really

Tony Wyss-Coray studies the impact of aging on the human body and brain. In this eye-opening talk, he shares new research from his Stanford lab and other teams which shows that a solution for some of the less great aspects of old age might actually lie within us all.

The problem with race-based medicine

Social justice advocate and law scholar Dorothy Roberts has a precise and powerful message: Race-based medicine is bad medicine. Even today, many doctors still use race as a medical shortcut; they make important decisions about things like pain tolerance based on a patient's skin color instead of medical observation and measurement. In this searing talk, Roberts lays

What really happens when you mix medications?

If you take two different medications for two different reasons, here's a sobering thought: your doctor may not fully understand what happens when they're combined, because drug interactions are incredibly hard to study. In this fascinating and accessible talk, Russ Altman shows how doctors are studying unexpected drug interactions using a surprising resource: search

How we'll fight the next deadly virus

When Ebola broke out in March 2014, Pardis Sabeti and her team got to work sequencing the virus's genome, learning how it mutated and spread. Sabeti immediately released her research online, so virus trackers and scientists from around the world could join in the urgent fight. In this talk, she shows how open cooperation was key to halting the virus ... and to

How my son's short life made a lasting difference

After Sarah Gray's unborn son Thomas was diagnosed with anencephaly, a terminal condition, she decided to turn her family's tragedy into an extraordinary gift and donate his organs to scientific research. In this tribute to life and discovery, she shares her journey to find meaning in loss and spreads a message of hope for other grieving families.

What you can do to prevent Alzheimer's

Alzheimer's doesn't have to be your brain's destiny, says neuroscientist and author of "Still Alice," Lisa Genova. She shares the latest science investigating the disease — and some promising research on what each of us can do to build an Alzheimer's-resistant brain.

A smarter, more precise way to think about public health

Sue Desmond-Hellmann is using precision public health — an approach that incorporates big data, consumer monitoring, gene sequencing and other innovative tools — to solve the world's most difficult medical problems. It's already helped cut HIV transmission from mothers to babies by nearly half in sub-Saharan Africa, and now it's being used to address alarming infant